@author : Kimberly Insigne [email protected]
Feb 19, 2018
Please don't hesistate to email me with any questions.
Here's a basic description of where the data lies and how you can use it in your own work.
To locate the raw read counts per bin:
- There is an Excel file with all of the read counts per bin for each construct.
- The version of the SNV library used in the main paper is located at
processed_data/snv/snv_v2_all_alignments.csv
- The data for the SRE library is located under
processed_data/sre/dhfr/dhfr_all_alignments.csv
andprocessed_data/sre/smn1/smn1_all_alignments.csv
for the two different intron backbones. - Raw sequencing data is not available at this time due to storage constraints but will be made public upon publication.
To located processed and cleaned data:
- For the SNV library, the Excel file is processed by
process_scripts/snv/snv_data_clean.R
and produces the fileprocessed_data/snv/snv_data_clean.txt
. This is probably the file you will want to work with, it contains the calculated exon inclusion index as well as information integrated from the reference (ref/snv/snv_ref_formatted_converted_original_seq.txt
) processed_data/snv/snv_simple_list.txt
contains a simplified list of the SDVs identified in the ExAC library and contains coordinates, the reference and alternate alleles, and the delta exon inclusion index.