Comments (4)
Hi,
You are seeing Signature H, because that wasn't able to be decomposed into COSMIC signatures. So it was reported as a new signature. All other De Novo Signatures were decomposed into the 15 COSMIC signatures.
from sigprofilerextractor.
Okay, got it - is the reason that is wasn't able to be decomposed into COSMIC signatures just because there are other signatures that are not represented by any of the COSMIC signatures?
from sigprofilerextractor.
Yes, you are correct.
from sigprofilerextractor.
Understood, thank you!
from sigprofilerextractor.
Related Issues (20)
- When running VCFs, ValueError: Error: More than 30% of mutations were skipped. HOT 2
- number of signatures in solution HOT 2
- UnicodeEncodeError: 'latin-1' codec can't encode characters in position 1-40: ordinal not in range(256) HOT 5
- Alexandrov FTP server not responding
- install own copy of genome HOT 1
- [Errno 2] No such file or directory HOT 3
- Cosine similarity for each COSMIC signature HOT 1
- calculate cosine similarity HOT 1
- Signature plots not being plotted for 4608 context extractions
- Inquiry Regarding sigProfilerExtractor Resource Requirements HOT 1
- interpretation for SBS 96D HOT 5
- SBS384 extraction problem HOT 5
- Strategies to improve cosine similarity per sample HOT 1
- error because of new pandas version HOT 1
- Minimum number of mutations or genome length. HOT 1
- Custom opportunities matrix HOT 8
- AttributeError: 'NoneType' object has no attribute 'keys (decomposition.py error) HOT 2
- Infinite loop HOT 1
- Issue with install HOT 2
- ValueError: operands could not be broadcast together with shapes (83,0) (0,0) HOT 3
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