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Hi there 👋

I'm an Associate Professor in Psychiatry, Harvard Medical School, and Associate Biophysicist, McLean Hospital and Director of the Technical and Instrumentation Core at the Brain Imaging Center. I received a BS in Physics from Yale University and a PhD in Biophysics from the University of California at Berkeley, back when dinosaurs roamed the Earth.

My training is in MR physics, and my PhD thesis is entitled “Three Dimensional Nuclear Magnetic Resonance Spectroscopic Imaging of Sodium Ions Using Stochastic Excitation and Oscillating Gradients”. If stochastic NMR with oscillating gradients is the solution to your problem, I'd gently suggest finding a different problem. However, in doing my thesis I discovered a love of thinking hard about noise, and writing absurdly complicated software at (or past) the level of my actual coding abilities.

I'm also the Director of the McLean Hospital Opto Magnetic Group, and my research is focused on multimodal acquisition and processing for hemodynamic quantitation and physiological denoising of BOLD and NIRS data.

  • I’m currently on a mission to try to convince people that they really should use rapidtide to properly denoise their fMRI and NIRS data. I get kind of fanatical about it. Double your SNR for no money!
  • I really like trying to find what I consider gaps in the open source fMRI processing infrastructure, and filling them with code.
  • Ask me about physiological noise, but only if you are either 1) actually interested or 2) need a sleep aid.

Blaise deB Frederick's Projects

capcalc icon capcalc

Various programs for processing and displaying coactivation patterns in fMRI data

checkerflash icon checkerflash

Psychopy code to generate flashing checkerboard stimuli

docker-opengl icon docker-opengl

Docker - Mesa 3D OpenGL Software Rendering (Gallium) - LLVMpipe, and OpenSWR Drivers

fmriprep icon fmriprep

fMRIprep is a functional magnetic resonance image pre-processing pipeline that is designed to provide an easily accessible, state-of-the-art interface that is robust to differences in scan acquisition protocols and that requires minimal user input, while providing easily interpretable and comprehensive error and output reporting.

micscriptlib icon micscriptlib

Routines to simplify the creation of neuroimaging proc scripts

nipype icon nipype

Workflows and interfaces for neuroimaging packages

niworkflows icon niworkflows

Common workflows for MRI (anatomical, functional, diffusion, etc)

phys2denoise icon phys2denoise

A collection of scripts to prepare physiology data for fMRI denoise

physioqc icon physioqc

Toolbox for physiological data (Automagic) Quality Control

picachooser icon picachooser

A fast lightweight gui tool for sorting components from a MELODIC probabilistic ICA analysis

pynirs icon pynirs

Routines for processing NIRS data

pysnirf icon pysnirf

A python library to read and write SNIRF (standard near infrared files)

qtpy icon qtpy

Provides an uniform layer to support PyQt5, PyQt4 and PySide with a single codebase

rapidtide icon rapidtide

rapidtide - a suite of programs for doing time lag correlation analysis on fMRI data

spikefix icon spikefix

Simple scripts for finding and removing spikes from fMRI datasets

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