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CNIO Bioinformatics Unit's Projects

beyondcell icon beyondcell

Beyondcell is a computational methodology for identifying tumour cell subpopulations with distinct drug responses in single-cell RNA-seq and Spatial Transcriptomics data.

breast-bcspatial icon breast-bcspatial

Code used to produce the final figures and tables of the study "Spatial Transcriptomics in Breast Cancer Reveals Tumour Microenvironment-Driven Drug Responses and Clonal Therapeutic Heterogeneity".

gotcha icon gotcha

Pipeline for processing of GoT-ChA genotyping data and downstream analysis

ssc-breast icon ssc-breast

A snakemake pipeline to generate the transcriptomic signatures of breast cancer drug susceptibility used in "Spatial Transcriptomics in Breast Cancer Reveals Tumour Microenvironment-Driven Drug Responses and Clonal Therapeutic Heterogeneity".

st-preprocess icon st-preprocess

Pipelines to preprocess 10x Visium data, including spot filtering and deconvolution, normalization and beyondcell score calculation.

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