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fabio-t avatar fabio-t commented on July 28, 2024

@lzj1769

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fabio-t avatar fabio-t commented on July 28, 2024
  • Uniprobe doesn't seem to provide plain-text annotation (maybe in SQL?). We exclude it for now.

  • Hocomoco, by far, is the best at providing both matrices and annotation. Both are plain text.

  • Jaspar provides all matrices, but doesn't provide plain-text annotation. I wrote a SQL query to extract the needed annotation from a big SQL dump they provide.

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fabio-t avatar fabio-t commented on July 28, 2024

49e17f7: finished proper query to convert jaspar annotation to something both useful to us, and compatible with hocomoco's annotation too.

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fabio-t avatar fabio-t commented on July 28, 2024

Script to get and convert the annotation done. The fields that I've kept, for now, are the following: motif name, gene name, family description and UniProt accession.

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fabio-t avatar fabio-t commented on July 28, 2024

Note for later: should we uppercase the genes in the MotifSet, or not?

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fabio-t avatar fabio-t commented on July 28, 2024

Deemed unnecessary with the changes in https://github.com/CostaLab/reg-gen/tree/feature/motif-script

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