Comments (2)
emdann
commented on August 28, 2024
- Select diseases: using pneumonia, cystic fibrosis, COPD and PF where samples are all in HLCA, and mix of cases with and without strong sc svidence enrichment (to test if fine annotation leads to finding more targets)
- Download HLCA data with fine & uniform annotations and pseudobulk
- Run DE analysis on HLCA pseudo-bulk annotations
- Compare enrichment on selected diseases
- Compare set of targets identified for different diseases
from sc_target_evidence.
emdann
commented on August 28, 2024
Another idea for fine vs coarse comparison: using celltypist organ models
from sc_target_evidence.
Related Issues (14)
- Update Cell Ontologies harmonization HOT 1
- Save overall similarity between cell types for each pseudo-bulk
- Toxicology/safety evidence
- API structure
- Differential expression utils
- Checking the cell annotations
- Plot diagnostics for DE analysis
- Intercept or no intercept for DE test on the cell types?
- Fix download of problematic stomach / brain files HOT 1
- Targeted analysis of lung diseases HOT 1
- Re-run workflow fixing issue with primary data filtering & updated cxg database
- Low quality annotation diseases
- How to obtain the original unaggregated cxg dataset HOT 2
Recommend Projects
-
React
A declarative, efficient, and flexible JavaScript library for building user interfaces.
-
Vue.js
🖖 Vue.js is a progressive, incrementally-adoptable JavaScript framework for building UI on the web.
-
Typescript
TypeScript is a superset of JavaScript that compiles to clean JavaScript output.
-
TensorFlow
An Open Source Machine Learning Framework for Everyone
-
Django
The Web framework for perfectionists with deadlines.
-
Laravel
A PHP framework for web artisans
-
D3
Bring data to life with SVG, Canvas and HTML. 📊📈🎉
-
Recommend Topics
-
javascript
JavaScript (JS) is a lightweight interpreted programming language with first-class functions.
-
web
Some thing interesting about web. New door for the world.
-
server
A server is a program made to process requests and deliver data to clients.
-
Machine learning
Machine learning is a way of modeling and interpreting data that allows a piece of software to respond intelligently.
-
Visualization
Some thing interesting about visualization, use data art
-
Game
Some thing interesting about game, make everyone happy.
Recommend Org
-
Facebook
We are working to build community through open source technology. NB: members must have two-factor auth.
-
Microsoft
Open source projects and samples from Microsoft.
-
Google
Google ❤️ Open Source for everyone.
-
Alibaba
Alibaba Open Source for everyone
-
D3
Data-Driven Documents codes.
-
Tencent
China tencent open source team.
from sc_target_evidence.