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Odd Prec? about esm HOT 6 CLOSED

facebookresearch avatar facebookresearch commented on August 30, 2024
Odd Prec?

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Comments (6)

rmrao avatar rmrao commented on August 30, 2024 1

Yes - in the paper we specifically consider short range contacts to be those in the range 5 < |i - j| < 12, rather than |i - j| > 5. Note this is consistent with CASP/etc. which refer to |i - j| > 5 as SR + MR + LR contacts, rather than specifically short-range contacts. This value can be quite low because there are often fewer than L short or medium range contacts, so it may be impossible to reach a precision of 1.

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nasserhashemi avatar nasserhashemi commented on August 30, 2024

I have checked the contact map over 25000 target based on single sequence using esm-b model; and the mean precision of long-range was lower than short-range as expected;

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227BaronChen avatar 227BaronChen commented on August 30, 2024

Okay, but why Table 1 and Table 2 in the paper are different? Did I make a mistake?

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nasserhashemi avatar nasserhashemi commented on August 30, 2024

I am not sure; I think, the termination of short-range has some kind of inconsistency; I think when people talked about short-range they consider any i and j which |i - j| > 5; however; in the paper they consider 5<|i-j|<12; I think it is the reason;
for example see the table 1 and 2 in the below paper:
https://academic.oup.com/bioinformatics/article/28/2/184/198108

but again, I am not sure

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nasserhashemi avatar nasserhashemi commented on August 30, 2024

yes, you are right, so the paper I mentioned was inconsistent:)

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tomsercu avatar tomsercu commented on August 30, 2024

seems like this is resolved - but feel free to open a discussion here!

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