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Avinash R's Projects

all1_panel_plots icon all1_panel_plots

A series of scripts to make panel plots for CNVs and regions of LOH across the genome.

arnav icon arnav

Mutation calling using a site-specific binomial model

cse232 icon cse232

Course notes for CSE 232 at Washington University

datasets icon datasets

A collection of awesome data sets to practice various kinds of analyses.

denovogear icon denovogear

A program to detect denovo-variants using next-generation sequencing data. (http://www.nature.com/nmeth/journal/v10/n10/full/nmeth.2611.html)

denovogear-legacy icon denovogear-legacy

Statistical model to detect de-novo mutations using sequencing data from trios and pairs.

dng_betabinomial_paired icon dng_betabinomial_paired

DeNovoGear with BetaBinomial likelihoods for paired sample mutation calling. For example this package can be used to do tumor vs normal comparisons. The BetaBinomial likelihood model has been shown to have a higher sensitivity and specificity compared to the binomial model.

fdr icon fdr

Control the false discovery rate using the Benjamini Hochberg procedure in C++

gms icon gms

The Genome Modeling System installer (BETA).

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