Comments (9)
Cell part projection morphogenesis is probably OK. Here there is a precisely controlled shape . There is a biological programme to create a specific shape (in each cell).
Mitochondrion seems quite different , they are derived from the ER, and then are maintained over multiple cell divisions by fission and fusion.
So we could just get rid of mitochondrion morphogenesis which is easy because it is in an isolated branch, and keeps mitochondrion organization annotation neater (this is more critical because it is a revived area of interest in the past year or too, a lot of uncharacterized unknowns are in here).
I don't know much about cell projection but I'd be inclined to keep "cell projection morphogenesis" and obsolete "cell part morphogenesis" as an unnecessary grouping term if GO:0070584 mitochondrion morphogenesis obsoletion is agreed. If that seems OK, I can do that.
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Hi @ValWood
We should always strive to look at these types of terms globally.
In this case, the hierarchy is like this:
I suggest:
- renaming cellular component morphogenesis to 'cellular anatomical entity morphogenesis, to match the top level in that branch
- obsolete 'cell part morphogenesis' with replace by cellular component morphogenesis/cellular anatomical entity morphogenesis
- Not sure we need 'cell projection morphogenesis, since all children are children of that term.
Thanks, Pascale
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Hi @ValWood happy with the suggestion to merge mito morph with mitochondrion organization.
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OK I will proceed with obsoletion/merge shortly.
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@pgaudet are you OK for me to merge "mitochondrial morphogenesis" into "mitochondrial organization"
and merge "cell part morphogenesis" into cellular component morphogenesis (since "cell projection morphogenesis" will be the only type, single inheritance)
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Sure
We should create a different ticket for the obsolete/replace of "cell part morphogenesis" with "cellular component morphogenesis" since it's more general.
Also, "cellular component morphogenesis" should be renamed "cellular anatomical structure morphogenesis" (and the LD adjusted accordingly)
Thanks, Pascale
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Action
merge
"mitochondrial morphogenesis" into "mitochondrial organization"
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This term has a comment, which I had not previously noticed:
Note that this term is intended for annotation of gene products involved in mitochondrial shape changes associated with development; an example is the morphogenesis of the Nebenkern during spermatogenesis.
and does not appear to reflect how is used.
(Also in this case why isn't it a descendent of 'sperm mitochondrion' organization?)
There is also a term
GO:0007287 Nebenkern assembly
Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern.
So I will proceed with the proposed obsoletion.
@hattrill should GO:0007287 Nebenkern assembly be a descendent of
'sperm mitochondrion' organization'?
are both terms required? maybe we could just relocate
GO:0007287 Nebenkern assembly and get rid of 'sperm mitochondrion' organization' as a "cell type + term"
Let me know what you think.
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add synonym
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Related Issues (20)
- Obsoletion request: trehalose biosynthesis in response to heat stress (GO:0090441) HOT 1
- Add check to prevent empty literal values HOT 1
- NTR: UDP-glucose biosynthetic process HOT 9
- Missing MetaCyc pathway xrefs (carbohydrate metabolism)
- NTR: [RNA glycosylation] HOT 1
- input/output chemicals on GO:0061624/R-HSA-70350 HOT 2
- 'glycogen biosynthetic process' parents HOT 3
- NTR's ??: additional subtypes of "isotype switching to IgG isotypes (GO:0048291)
- Obsoletion request:GO:0044255, GO:0097384, GO:0044242 cellular lipid metabolic, biosynthetic and catabolic process terms
- Review of glycosaminoglycan metabolic process (GO:0030203) and proteoglycan metabolic process (GO:0006029) branches HOT 1
- Proposed changes to cellular anatomical entity from COB meeting HOT 3
- calcium-activated cation channel activity (GO:0005227) HOT 1
- Textual definition update: GO:0043490 malate-aspartate shuttle
- Obsoletion with replacement: GO:0006948 induction by virus of host cell-cell fusion & GO:0060140 modulation by virus of syncytium formation via plasma membrane fusion
- Response to phosphate/ nutrient homeostasis HOT 8
- go.obo and go-basic.obo have different data-version in snapshot HOT 2
- GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidine should tRNA-specific adenosine-34 deaminase activity be a descendant? HOT 2
- Missing parent: GO:0106340 tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase activity
- NTR: negative regulation of acetyl-CoA biosynthetic process from pyruvate
- NTR: histone H3K4 deacetylase activity, NAD-dependent
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