Comments (3)
Although maybe we need to change the definition/term, because this moiety is added to all polymerase II transcripts:
mRNA, ncRNA and some of the snoRNA/snRNA
Or maybe we need a generic term that isn't coupled to translation initiation....
This term, as it stands should be relabelled
- mRNA methylguanosine-cap decapping
and add - mRNA catabolic process added as superclass (cannot be added, see below)
from go-ontology.
- changed to mRNA methylguanosine-cap decapping to match the definition (if we need other molecule decapping we can add it later, but since this is in the context of translation, and since other caps appear to be further processed so the removal will apply to a different mature cap structure this is probably the only methylguanosine-cap decapping)
I can't add superclass mRNA catabolic process because
"The mRNA cap decapping, on the other hand, is a regulatory step in which the 5' cap structure of mRNA is removed. This process can lead to mRNA degradation, but it can also be a reversible and regulatory event, allowing the mRNA to undergo further processing or translation repression without degradation."
- added "mRNA metabolic process" instead (has RNA decapping already)
from go-ontology.
this was done
from go-ontology.
Related Issues (20)
- Add check to prevent empty literal values HOT 1
- NTR: UDP-glucose biosynthetic process HOT 9
- Missing MetaCyc pathway xrefs (carbohydrate metabolism)
- NTR: [RNA glycosylation] HOT 1
- input/output chemicals on GO:0061624/R-HSA-70350 HOT 2
- 'glycogen biosynthetic process' parents HOT 3
- NTR's ??: additional subtypes of "isotype switching to IgG isotypes (GO:0048291)
- Obsoletion request:GO:0044255, GO:0097384, GO:0044242 cellular lipid metabolic, biosynthetic and catabolic process terms
- Review of glycosaminoglycan metabolic process (GO:0030203) and proteoglycan metabolic process (GO:0006029) branches HOT 1
- Proposed changes to cellular anatomical entity from COB meeting HOT 3
- calcium-activated cation channel activity (GO:0005227) HOT 1
- Textual definition update: GO:0043490 malate-aspartate shuttle
- Obsoletion with replacement: GO:0006948 induction by virus of host cell-cell fusion & GO:0060140 modulation by virus of syncytium formation via plasma membrane fusion
- Response to phosphate/ nutrient homeostasis HOT 8
- go.obo and go-basic.obo have different data-version in snapshot HOT 2
- GO:0016814 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidine should tRNA-specific adenosine-34 deaminase activity be a descendant? HOT 2
- Missing parent: GO:0106340 tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase activity
- NTR: negative regulation of acetyl-CoA biosynthetic process from pyruvate
- NTR: histone H3K4 deacetylase activity, NAD-dependent HOT 1
- Obsoletion request: GO:0052201 response to symbiont defenses
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from go-ontology.