Comments (4)
id: GO:0045486
name: naringenin 3-dioxygenase activity
namespace: molecular_function
def: "Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2." [EC:1.14.11.9]
synonym: "(2S)-flavanone 3-hydroxylase activity" RELATED [EC:1.14.11.9]
synonym: "flavanone 3-beta-hydroxylase activity" RELATED [EC:1.14.11.9]
synonym: "flavanone 3-dioxygenase activity" RELATED [EC:1.14.11.9]
synonym: "flavanone 3-hydroxylase activity" RELATED [EC:1.14.11.9]
synonym: "flavanone 3beta-hydroxylase activity" RELATED [EC:1.14.11.9]
synonym: "flavanone synthase I activity" RELATED [EC:1.14.11.9]
synonym: "flavanone,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating)" RELATED [EC:1.14.11.9]
synonym: "naringenin 3-hydroxylase activity" RELATED [EC:1.14.11.9]
synonym: "naringenin,2-oxoglutarate:oxygen oxidoreductase (3-hydroxylating) activity" RELATED [EC:1.14.11.9]
xref: EC:1.14.11.9
xref: MetaCyc:NARINGENIN-3-DIOXYGENASE-RXN
xref: RHEA:18621
is_a: GO:0016706 ! 2-oxoglutarate-dependent dioxygenase activity
EC:1.14.11.9/RHEA:18621 is for the more general reaction:
flavanone 3-dioxygenase
2-oxoglutarate + a (2S)-flavan-4-one + O2 <=> a (2R,3R)-dihydroflavonol + CO2 + succinate
- change GO name and def to match EC/RHEA
- Change MetaCyc to 1.14.11.9-RXN
from go-ontology.
Need to remove H+ from these reaction defs to match RHEA:
[Term]
id: GO:0102533
name: genkwanin 4'-O-methyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine = apigenin 4',7-dimethyl ether + S-adenosyl-L-homocysteine + H+." [RHEA:73263]
xref: MetaCyc:RXN-14750 {source="skos:exactMatch"}
xref: RHEA:73263 {source="skos:exactMatch"}
is_a: GO:0008168 ! methyltransferase activity
property_value: term_tracker_item "#28199" xsd:anyURI
[Term]
id: GO:0102439
name: 3',4',5'-trimethylmyricetin 7-O-methyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: 3',4',5'-O-trimethylmyricetin + S-adenosyl-L-methionine = 7,3',4',5'-O-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+." [RHEA:74739]
xref: MetaCyc:RXN-13916 {source="skos:exactMatch"}
xref: RHEA:74739 {source="skos:exactMatch"}
is_a: GO:0008168 ! methyltransferase activity
property_value: term_tracker_item "#28199" xsd:anyURI
id: GO:0102440
name: 3',4',5'-trimethylmyricetin 3-O-methyltransferase activity
namespace: molecular_function
def: "Catalysis of the reaction: 3',4',5'-O-trimethylmyricetin + S-adenosyl-L-methionine = 3,3',4',5'-O-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+." [RHEA:74771]
xref: MetaCyc:RXN-13918 {source="skos:exactMatch"}
xref: RHEA:74771 {source="skos:exactMatch"}
is_a: GO:0008168 ! methyltransferase activity
property_value: term_tracker_item "#28199" xsd:anyURI
from go-ontology.
After checking with RHEA:
- add RHEA:30003 to GO:0047270
- add RHEA:30015 to GO:0008919
- change RHEA on GO:0033230 from RHEA:32795 to RHEA:29783
- GO:0008718 - MetaCyc:RXN-11193 and EC:1.4.5.1 are narrowMatch, RHEA:18125 is exactMatch
- GO:0102624 - add RHEA:73239 and improve def
- GO:0102447 - add RHEA:73271 and improve def
- GO:0010945 - make RHEA:50044, RHEA:64988, MetaCyc:RXN-10811 narrowMatch
from go-ontology.
id: GO:0050550
name: pinene synthase activity
namespace: molecular_function
def: "Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate. This reaction can produce both alpha-pinene and beta-pinene." [PMID:21385377, PMID:23679205]
synonym: "(-)-(1S,5S)-pinene synthase activity" NARROW [EC:4.2.3.120]
synonym: "alpha-pinene synthase activity" NARROW [EC:4.2.3.119]
synonym: "beta-geraniolene synthase activity" RELATED [EC:4.2.3.120]
synonym: "beta-pinene synthase activity" NARROW [EC:4.2.3.120]
xref: EC:4.2.3.119 {source="skos:narrowMatch"}
xref: EC:4.2.3.120 {source="skos:narrowMatch"}
xref: MetaCyc:RXN-5106 {source="skos:narrowMatch"}
xref: MetaCyc:RXN-5107 {source="skos:narrowMatch"}
xref: RHEA:25488 {source="skos:narrowMatch"}
xref: RHEA:25496 {xref="skos:narrowMatch"}
is_a: GO:0010333 ! terpene synthase activity
property_value: term_tracker_item "#26207" xsd:anyURI
- Add additional xrefs as narrowMatch: EC:4.2.3.121 = RHEA:32575 = RXN-8563, EC:4.2.3.122 = RHEA:32579 = RXN-8564
- Also, modify def to indicate all forms that are covered by this single GO term.
- fix {xref="skos:narrowMatch"} line
from go-ontology.
Related Issues (20)
- Catalytic activity terms with no cross references - terms in scope for GO
- Add check for database definition cross references to also be a general cross reference HOT 2
- Catalytic activity (MF) terms with multiple MetaCyc mappings
- Pathway (BP) terms with multiple MetaCyc mappings
- carbonyl reductase (NADPH) activity (GO:0004090)
- alcohol dehydrogenase/aldo-keto reductase hierarchy HOT 1
- EC mapping GO:0103045 | methione N-acyltransferase activity | IEA with 2.3.1.1 | GO_REF:0000003 HOT 2
- typo in term nameGO:0103045 | methione N-acyltransferase activity
- Obsoletion request: GO:0035629 N-terminal protein amino acid N-linked glycosylation; GO:0042543 protein N-linked glycosylation via arginine
- Obsoletion request: GO:0071170 | site-specific DNA replication termination GO:0071946 | cis-acting DNA replication termination
- Missing parent: polyphosphate import into vacuole HOT 1
- Obsoletion request: GO:0030242 autophagy of peroxisome HOT 3
- Obsoletion request: GO:0102028 cystathionine gamma-synthase activity (acts on O-phosphohomoserine) HOT 1
- True path violations under NON proteinogenic amino acid metabolic process HOT 6
- Obsoletion request: Wnt signaling pathway involved in x
- Query RNA (cytidine(32)/uridine(32)-2'-O)-methyltransferase
- Missing parent: GO:0000162 tryptophan biosynthetic process HOT 5
- remove enzyme xrefs from obsolete terms
- broad/narrow xref qualifiers are not exported in OBO JSON format
- Obsoletion request: actin filament-based process
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from go-ontology.