Comments (2)
Good question
Unfortunately LDSC requires genome-wide data. For a single locus it will return extremely noisy estimates (basically just noise), and the standard error estimates will also be wrong...
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I see, that makes sense. Thanks!
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Related Issues (20)
- LD matrix snps HOT 1
- There appear to be 1 leaked semaphore objects to clean up at shutdown warnings.warn('resource_tracker: There appear to be %d ' HOT 3
- Can extract_snpvar.py accept sumstats in hg38 coordinates instead of hg19? HOT 2
- per-SNP heritability? HOT 3
- Test_polyfun.py failed: extract_snpvar command failed HOT 2
- Flag --n of finemapper.py confused `conda run -n polyfun` HOT 4
- susie_suff_stat no longer accept bhat input HOT 2
- LD matrix genome assembly HOT 1
- Locus has no credible set HOT 1
- Missing LD files HOT 1
- Some question about "best-practice recommendations" in article HOT 7
- Some problems in Computing LD-scores using existing functional annotation files HOT 8
- Missing SNPs in merging summary statistics with reference panel HOT 1
- TypeError: __init__() got an unexpected keyword argument 'normalize' HOT 6
- AttributeError: module 'networkx' has no attribute 'from_numpy_matrix' when I use arg --hess HOT 4
- The warning: IBSS algorithm did not converge in 100 iterations! HOT 2
- Scaled prior variance should be no greater than 1 when standardize = TRUE HOT 4
- Bgen input with an error caused by an incorrect variable invocation. HOT 2
- Issues on the number of chromosomes in different species HOT 2
- a question about Polypred+ HOT 7
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