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How adapter trimming works? about fastp HOT 2 CLOSED

opengene avatar opengene commented on July 25, 2024
How adapter trimming works?

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Comments (2)

sfchen avatar sfchen commented on July 25, 2024

Adapters only exist in 3' end.
Adapter trimming only cuts the adapters, but will not discard the reads.

For single-end data:
1, fastp is like cutadapt, but faster. Error tolerance is enabled. One mismatch is allowed for 8 bp overlap.
2, if part of adapter matches the tail of the read, the adapter is trimmed.

For paired end data:
Adapters is detected using overlap analysis. See the AfterQC paper.

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sfchen avatar sfchen commented on July 25, 2024

Closing this since this is not an issue

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