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Weird translocation results about mumandco HOT 1 OPEN

MyBiscuit avatar MyBiscuit commented on May 29, 2024
Weird translocation results

from mumandco.

Comments (1)

SAMtoBAM avatar SAMtoBAM commented on May 29, 2024

Hi there
Could you share an SVG of the whole genome alignment?
What is within these regions
Just a simple guess, most likely these regions across the different chromosomes contain shared repeats and therefore MUM&Co is finding alignments that bridge these chromosomes and interpreting it as a translocation. Have you tried increasing the -minlen?

from mumandco.

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