Name: Lab for Proteoform Systems Biology
Type: Organization
Bio: At the Sheynkman Lab, we study disease-relevant protein forms, or “proteoforms”, by integrating cutting-edge analytical and computational approaches from genomi
Blog: https://med.virginia.edu/sheynkman-lab/
Lab for Proteoform Systems Biology's Projects
"Surf" the biological network, from genome to transcriptome to proteome and back to gain insights into human disease biology.
This repository reproduces the analysis for biosurfer tool
This code repository uses the Biosurfer tool (old version) to conduct NMD and protein truncation analysis for long-read bone proteogenomics project.
Looking at things related to data from https://www.nature.com/articles/s41587-023-01714-x#Sec24
HUVEC analysis analyzing proteogenomic data generated from long-read transcriptomic sequencing and bottom-up mass spec data
Nextflow implementation of IsoSeq3
A workflow for enhanced protein isoform detection through integration of long-read RNA-seq and mass spectrometry-based proteomics.
Comparison of all available PDB chains (human) to the alternative isoforms in GENCODE.
Shay's splice event to isoform integration pipeline
A docker image to run SQANTI3
Repository of SQANTI3 tool for Quality Control of Long-Read Defined Transcriptomes
Pipeline to map sQTLs to protein isoforms
This repository contains the source code for the tappAS application. See README for details.