Vital Sign Futures? about synthea

[dehall]

I wish I could say we had a master plan all laid out, but unfortunately we aren't there yet. I do believe it would be ideal to have all Vital Signs set by GMF modules and not in the ruby modules, the reason we haven't gone down that path is that many of the vital sign values are based on formulas which the GMF isn't able to represent.

For instance, to estimate creatinine clearance for diabetes we use the formula Est. Creatinine Clearance = [[140 - age(yr)]*weight(kg)]/[72*serum Cr(mg/dL)] (ref: http://www.mcw.edu/calculators/creatinine.htm)

We're thinking about ways to potentially represent these kinds of formulas within the GMF, and we welcome any community suggestions.

[jeffeastman]

I'm working on a module to initialize the vital signs and then adjust their trajectories on a (monthly) bases. But yeah, we need formulas for that so working on them too.

I'll let you know how it works out.

[jeffeastman]

Here's the start of a module that can be edited to set initial values for all of the vitals. It then iterates monthly to adjust them. Way too simple minded but its a start. I've also added a simple Expression mechanism that is adequate to calculate the creatinine clearance and a new expression field on VitalSign that, if set, will evaluate the expression to set the next value of the vital. This version only adjusts it by - 1.0..1.0 so more work is needed for realism.

vital_signs.json.txt

Here's an Expression that will evaluate the creatinine clearance, just so you can see a bit more about Expressions. For example, Formulas are simple binary operators and Primitives can either be single values, the names of a vital (plus age and gender tests) or a Range.

Hmmm, the "" operators should be *. It seems the wiki is morphing them.

{
"type": "Formula",
"left": {
"type": "Formula",
"left": {
"type": "Formula",
"left": {
"type": "Formula",
"left": {
"type": "Primitive",
"value": 140.0
},
"operator": "-",
"right": {
"type": "Primitive",
"sign": "Age(yr)"
}
},
"operator": "",
"right": {
"type": "Primitive",
"sign": "Weight"
}
},
"operator": "/",
"right": {
"type": "Formula",
"left": {
"type": "Primitive",
"value": 72.0
},
"operator": "",
"right": {
"type": "Primitive",
"sign": "Creatinine"
}
}
},
"operator": "",
"right": {
"type": "Formula",
"left": {
"type": "Primitive",
"sign": "isMale"
},
"operator": "+",
"right": {
"type": "Formula",
"left": {
"type": "Primitive",
"value": 0.85
},
"operator": "",
"right": {
"type": "Primitive",
"sign": "isFemale"
}
}
}
}

[jeffeastman]

I've got a more complete vital_signs module and am working with my management to release it. Closing this for now.