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Systems and Synthetic Biology at Chalmers University of Technology's Projects

bayesiangem icon bayesiangem

This repository contains code and data needed to replicate the analysis carried out in the manuscript Li G, et al. 2020.

cancerproteinsecretionml icon cancerproteinsecretionml

A collection of scripts to analyze cancer transcriptomics data using various statistical and machine-learning approaches.

candia icon candia

Canonical Decomposition of Data-Independent-Acquired Spectra

cellfactory-ecyeastgem icon cellfactory-ecyeastgem

Code and data for in silico strain design for enhanced production of +100 typical bio-products with yeast as a cell-factory. Predictions are based on the ecYeastGEM model avaiable at ecModels.

clpapi icon clpapi

R Interface to C API of COIN-OR Clp

cofactoryeast icon cofactoryeast

Integration of cofactors with proteome-constrained model of Saccharomyces cerevisiae

comparativestudycrabtreeeffect icon comparativestudycrabtreeeffect

Collection of data and scripts for the study "Adaptations in metabolism and protein translation give rise to the Crabtree effect in yeast"

dlkcat icon dlkcat

Deep learning and Bayesian approach applied to enzyme turnover number for the improvement of enzyme-constrained genome-scale metabolic models (ecGEMs) reconstruction

dsave-m icon dsave-m

Matlab code for the paper "Dissecting Cell-to-Cell Variation in Single-cell RNA-Seq Data"

dsave-r icon dsave-r

R Package DSAVE (Down-SAmpling based Variation Estimation). The package operates on single-cell RNA-Seq data and is useful for finding misclassified cells, comparing the outcome of clustering methods, figuring out minimum clustering sizes to get the same variation as for bulk, and comparing the technical variation across datasets. The package is compatible with Seurat.

ecfactory icon ecfactory

A constraint-based method for prediction of metabolic engineering targets using ecModels of metabolism

ecm_yeast icon ecm_yeast

Automated pipeline for full kinetic parameterization of a reduced model for Saccharomyces cerevisiae's central carbon metabolism.

ecmodels icon ecmodels

A container for all enzyme constrained models created by GECKO.

enzymeconstrained_humanmodels icon enzymeconstrained_humanmodels

Collection of scripts for enhancing humanGEM based models with kinetic and proteomics constraints and specialized simulation utilities.

epo_gfp icon epo_gfp

Transcriptome analysis of EPO- and GFP-producing HEK293 Cell-lines

falconet icon falconet

The FALCONET R package enables to build and visualise metabolic maps of GEM automatically with aid of cellDesigner 4.4 and R platform

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