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Svetlana Panina's Projects

ctd_length_polii_pausing_alternative_splicing icon ctd_length_polii_pausing_alternative_splicing

Code and processed data used to calculate whole-genome (Pausing Index) and whole-transcriptome (AS - alternatively spliced genes' lengths) metrics. We compared these metrics in wild-type cells vs. cells with transient expression of "shortened" CTD (C-terminal domain) RNA polymerase II (Pol II).

polii_metrics icon polii_metrics

Calculation of RNA Pol II metrics using Chip-Seq data: Processivity [PMID:32917631], Traveling Ratio [PMID:38521065] and Pausing Index [PMID:27259512].

rest_expression_gbm icon rest_expression_gbm

Building predictive models to identify dependency of glioblastoma tumor (GBM) on REST - RE-1 silencing transcription factor

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