pRoloc
is a Bioconductor package for the analysis of experimental spatial
proteomics data. It is available from Bioconductor >= 2.12
and
requires R (>= 3.0.0)
.
The preferred installation procedure uses the Bioconductor infrastructure:
source("http://bioconductor.org/biocLite.R")
biocLite("pRoloc")
You can also install the associated data package
pRolocdata
with multiple experimental data sets.
Gatto L, Breckels LM, Wieczorek S, Burger T, Lilley KS. Mass-spectrometry based spatial proteomics data analysis using pRoloc and pRolocdata. Bioinformatics. 2014 Jan 11. [Epub ahead of print] PubMed PMID: 24413670.
Breckels LM, Gatto L, Christoforou A, Groen AJ, Lilley KS, Trotter MW. The effect of organelle discovery upon sub-cellular protein localisation. J Proteomics. 2013 Aug 2;88:129-40. doi: 10.1016/j.jprot.2013.02.019. Epub 2013 Mar 21. PubMed PMID: 23523639.
Gatto L., Breckels L.M., Burger T, Nightingale D.J.H., Groen A.J., Campbell C., Mulvey C.M., Christoforou A., Ferro M., Lilley K.S. "A foundation for reliable spatial proteomics data analysis", Mol Cell Proteomics. 2014 May 20. publisher