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glennhickey avatar glennhickey commented on September 17, 2024

Yeah, it would be handy to see differences in the reads that are not in the graph. This is a hard problem in general, but for SNPs it shouldn't be too bad. A SNP Edit in the GAM would look like

 {"to_length": 1, "from_length": 1, "sequence": "T"}

and in this case, the display should print a T at the appropriate position on the read. Presumably small inserts could be done in a similar manner by printing the sequence (or maybe insertion length). They look like (no from_length or from_length 0):

 {"to_length": 2, "sequence": "T"}

Deletes seem much harder as you would have to display a new edge to the graph. Deletion edits have the to_length field set to 0

 {"from_length": 2}

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wolfib avatar wolfib commented on September 17, 2024

How about displaying deletions by changing the read color from red to reddish transparent in the relevant region and not adding any extra edges?

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adamnovak avatar adamnovak commented on September 17, 2024

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adamnovak avatar adamnovak commented on September 17, 2024

We don't do anything special for this, but I don't think we really need to. Seeing several mismatches/indels at the same position is enough.

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