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Hi there, I'm Chris.

I am currently a lead scientist at Deep Genomics in Toronto. My work involves using machine learning and AI to identify causal drug targets from human genetics data. I previously completed my DPhil working with Gerton Lunter and Thomas Milne at the University of Oxford. Check out my website for a breakdown of previous projects and repositories of interest.

Christopher Cole's Projects

aavcf icon aavcf

Swap allels to ancestral / derived in a VCF.

allerid icon allerid

A goldi-based shiny app to identify allergens.

blda icon blda

Weighted latent dirichlet allocation for bulk ATAC-seq

ccole icon ccole

Wrappers and convenience functions either not yet included in a package or for personal use.

cistopic icon cistopic

cisTopic: Probabilistic modelling of cis-regulatory topics from single cell epigenomics data

cookbook icon cookbook

Flask cookbook application automatically deployed to Github pages

corge icon corge

Evaluation of Simultaneous Inference Methods for the Human Genome.

deepstab icon deepstab

Deep learning prediction of cell-type specific RNA stability.

dotfiles icon dotfiles

System configurations for Arch Linux, OSX, and CentOS 6.8

epic_rpg_converter icon epic_rpg_converter

A Discord bot for converting between resources in Epic RPG (another Discord bot).

ggsource icon ggsource

Easily open the file used to generate an exported PDF from R / ggplot2.

goldi icon goldi

R Package for Gene Ontology Label Discernment and Identification.

gwas_sim icon gwas_sim

Simulate a mixed-population GWAS for use in training exercises.

ima3_input icon ima3_input

A Snakemake pipeline for creating IMa3 input from a VCF file via the Popgen Pipeline Platform.

impute icon impute

Automated imputation pipeline for arbitrary dataset and reference panels.

lanceotron icon lanceotron

Command-line interface to the LanceOTron deep learning peak caller

ldsc icon ldsc

LD Score Regression (LDSC)

mchg icon mchg

Validation of Multiple Comparisons techniques for the human genome

polyfun icon polyfun

PolyFun (POLYgenic FUNctionally-informed fine-mapping)

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