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How to prepare the input Hi-C data?

I found that there is many negetive values in the example contact data. I wonder how to prepare the input Hi-C data from contact matrix.

chrom1 start1 end1 chrom2 start2 end2
1 chr19 30683824 30683825 chr19 45631573 45631574
2 chr19 30617472 30617473 chr19 45606509 45606510
3 chr19 30669904 30669905 chr19 45606508 45606509
4 chr19 30694599 30694600 chr19 45644855 45644856
5 chr19 30438239 30438240 chr19 45414363 45414364
6 chr19 30470215 30470216 chr19 45389373 45389374
hic.example_project.example_dataset.s... intervalID
1 -33.8 221
2 -28.8 221
3 -30.8 221
4 -32.8 221
5 -37.3 221
6 -35.3 221

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