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An R package for T cell receptor repertoire advanced data analysis.

Home Page: https://imminfo.github.io/tcr/

R 95.34% C++ 4.66%

tcr's Introduction

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tcR

tcR is a platform designed for TCR repertoire data analysis in R after preprocessing data with tools for CDR3 extraction and gene segments aligning (MiTCR, MiGEC, ImmunoSEQ, IMSEQ, etc.). With the power and flexibility of R language and procedures supported by tcR users can perform advanced statistical analysis of TCR repertoires. The package was published in BMC Bioinformatics:

Nazarov et al., tcR: an R package for T cell receptor repertoire advanced data analysis

See tcR website for more information, manual and examples: http://imminfo.github.io/tcr/

If you have any questions, suggestions or bug reports, feel free to raise an issue here: https://github.com/imminfo/tcr/issues

Warning! tcR internally expects columns with nucleotide and amino acid CDR3 sequences and columns with gene segments to have character class, not factor class. Use stringsAsFactors=FALSE parameter if you use R functions for parsing files with tables (.csv, .xls and others).

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