hmjeon / daedalus2-pub

DAEDALUS2-pub

DAEDALUS2-pub is the public version of DAEDALUS2. We will ditribute DAEDALUS2 version, which is software package written in FORTRAN 90/95 that enables the automated convertion of computer-generated design files into DNA sequences. These DNA sequences can be subsequently synthesized and mixed to fold DNA DX-based wireframe 3D lattices with high fidelity.

• Pure Fortran library for modern Fortran project
• Free and open source (GNU General Public License, version 3.0)
• Fully automatic procedure of the sequence design for scaffolded DNA DX-based wireframe lattices
• Importing GEO (geometry file format for DAEDALUS2-pub) and PLY file formats as an input
• Exact edge-lengths to design highly asymmetric and irregular shapes
• JSON output for editing staple paths and sequences from caDNAno
• 3D visual outputs by UCSF Chimera
• Pre-defined target geometries
• User-friendly TUI (Text-based User Interface)
• Online web resources and release packages for Microsoft Windows and Mac OS

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Online Portal | Outputs | Compiling Code | Copyrights

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Online Portal

http://DAEDALUS-dna-origami.org/

In addition to the source code and pre-compiled binaries available here, we also offer an online web application with all the functionality found in the downloaded version. By submitting the same inputs (PLY, GEO, IGS, or SVG input CAD files), the web service will return the same file output as the downloaded version.

Outputs

• The *.csv file generated by DAEDALUS2 contains final staple sequences.
• The *.bild and *.json generated by DAEDALUS2 can be opened by UCSF Chimera and caDNAno.
• The atomic model (PDB) can be generated by *.cndo file using the atomic model generator written by Dr. Keyao Pan.

Compiling Code

git clone https://github.com/hmjeon/DAEDALUS2-pub.git

Requirements to compile from source:

• Intel Fortran compiler: Intel Parallel Studio XE 2016, 2017 or 2018
• Compiling the DAEDALUS2 sources require Intel Fortran. Free Intel (R) Software Development Tools are available for qualified students, educators, academic researchers and open source contributors, see the details.
• The Intel Fortran compiler supports all of the features of the Fortran 90, Fortran 95, Fortran 2003 standards and most of Fortran 2008. It also supports some draft Fortran 2018 features.
• We provide MakeFile which is a simple way to organize code compilation of DAEDALUS2.

Copyrights

• Author
  Dr. Hyungmin Jun ( Personal web | e-mail )

• License
  DAEDALUS2-pub is an open-source software distributed under the GPL license, version 3

Anyone is interest to use, to develop or to contribute to DAEDALUS2 is always welcome!

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