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This is a guide to the code and data for the paper Mondragón-González, S. L., Schreiweis C, C., & Burguière E, E. (2024). Closed-loop recruitment of striatal parvalbumin interneurons prevents compulsive-like grooming behaviours. Nature Neuroscience

Home Page: https://www.nature.com/articles/s41593-024-01633-3

artificial-neural-networks local-field-potentials closed-loop-control data-science electrophysiological-data

2024_mondragon-gonzalez_natureneuroscience's Introduction

Closed-loop recruitment of striatal interneurons prevents compulsive-like grooming behaviours.

This is a guide to the code and data for the paper Mondragón-González, S. L., Schreiweis C, C., & Burguière E, E. (2024). Closed-loop recruitment of striatal parvalbumin interneurons prevents compulsive-like grooming behaviours. Nature Neuroscience. Link to Paper. Each listed repository is dedicated to a specific type of analysis or dataset. Please follow the links provided to explore the repositories in detail.

Table of Contents


Repository 1: Closed-loop - TriFilterNet

Description: Designed to detect pre-grooming events in mice by analyzing local field potential (LFP) recordings. It uses triangular filters for feature selection, reducing data to a matrix of decorrelated coefficients. These coefficients are the input for an artificial neural network to classify behavioral states. It includes its own demo data.

Repository 2: Data Set 1

Description: It features the electrophysiological recordings and the associated grooming markers used in the paper to asses the closed-loop algorithm. The data is compressed and available at the Open Science Framework.

Repository 3: Analysis LFP

Description: This repository contains the local field potential analysis scripts and functions.

Repository 4: Data Set 2

Description: It features the electrophysiological recordings in the mice's orbitofrontal cortex around grooming events. The data is available at the Open Science Framework.


Citation

If you use this code or data we kindly ask you to cite our work.

  • Data:

(APA style) Mondragón-González, S. L. (2024, March 26). 2024_Mondragon-Gonzalez_NatureNeuroscience. https://doi.org/10.17605/OSF.IO/KDMJT

  • Article: Mondragon et al 2024: DOI

@article{Mondragon2024, title = {Closed-loop recruitment of striatal interneurons prevents compulsive-like grooming behaviours}, author = {Sirenia Lizbeth Mondragón-González and Christiane Schreiweis and Eric Burguière}, journal = {Nature Neuroscience}, year = {2024}, url = {https://www.nature.com/articles/s41593-024-01633-3}}

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