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General question about higashi HOT 4 CLOSED

ma-compbio avatar ma-compbio commented on August 16, 2024
General question

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Comments (4)

tarak77 avatar tarak77 commented on August 16, 2024 1

Ok I will try it now

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ruochiz avatar ruochiz commented on August 16, 2024

Hi,

Thanks for your interest. It would be possible, especially when the coverage for each cell is relatively higher. For a dataset with smaller number of cells, It would also be easier to define subclusters based on one chromosome or a part of the chromosome of interest instead of whole genome. But of course, it depends on the composition of the cell population as well.

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ruochiz avatar ruochiz commented on August 16, 2024

Great. If you don't mind, could you wait for a day or so? I'm updating the code base with a major speed improvement today, which I believe would enhance your experiences with Higashi a lot. 😄

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tarak77 avatar tarak77 commented on August 16, 2024

Sounds good! I will just try using scHiCluster for today then.

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