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A Shiny R project to ease the statistical validation of analytical methods

License: GNU General Public License v3.0

R 0.30% HTML 99.70%
analytical-chemistry hplc pharmaceuticals r shiny-r statistical-analysis validation

r_validr's Introduction

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To cite ValidR :

Frédéric Marçon. (2023). marconfr/R_VALIDR: v1.0 (v1.0). Zenodo. https://doi.org/10.5281/zenodo.7706081

Analytical chemistry app written in shiny / R to ease the validation of method of dosing

-> ValidR Matrix : Detection of matrix effects

Based on regression analysis to detect of significant variations in intercepts or slopes

-> ValidR Assay : Method validation with accuracy profiles

Based on the tolerance intervals and accuracy profiles, which guarantee that a pre-defined proportion of future measurements obtained with the method will be included within the acceptance limits.

 ┌─────────────────────┐     ╔════════════════╗       ┌──────────────────────┐
 │MATRIX_TEMPLATE.XLSX │────▶║  ValidR Matrix ║──────▶│ REPORT_MATRIX.html   │
 └─────────────────────┘     ╚════════════════╝       └──────────────────────┘
                                                                            
                                                      ┌──────────────────────┐
                                                  ┌──▶│ REPORT_ASSAY.html    │
 ┌─────────────────────┐     ╔════════════════╗   │   └──────────────────────┘
 │ ASSAY_TEMPLATE.XLSX │────▶║  ValidR Assay  ║───┤                         
 └─────────────────────┘     ╚════════════════╝   │   ┌──────────────────────┐
                                                  └──▶│REPORT_ASSAY_1CAL.html│
                                                      └──────────────────────┘

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