GithubHelp home page GithubHelp logo

ldnfsgb's Introduction

LDNFSGB:Predicting lncRNA-disease associations using network feature similarity and gradient boosting

First, we construct a feature vector to extract similarity information of different lncRNAs and diseases. Then, an autoencoder is used to reduce the dimensionality of the feature vector. Finally, the gradientboosting classifier is used to predict lncRNA-disease associations.

#Autoencoder.py This part is mainly to reduce the dimensionality of the sample features.

#Gradientboosting.py It is mainly used for prediction of lncRNA-disease association. At the same time, this part provides the performance evaluation of the model under 10-fold CV including AUC, accuracy, sensitive, precision, specificity and ROC curve drawing.

The original datasets used in this study are available from the corresponding references.

References Zhang, Y., Ye, F., Xiong, D. et al. LDNFSGB: prediction of long non-coding rna and disease association using network feature similarity and gradient boosting. BMC Bioinformatics 21, 377 (2020). https://doi.org/10.1186/s12859-020-03721-0

ldnfsgb's People

Contributors

mlmip avatar yyyyyefei avatar

Stargazers

 avatar  avatar

ldnfsgb's Issues

呃呃

就这本科生大作业水平的代码也敢在论文里贴链接?屁创新没有,代码也不敢给全,恐怕自己都不知道数据要怎么跑,直接把降维的特征塞模型里边就能fit出0.93的AUC?你是真的牛批,居然直接就把特征扔进去,属实难绷。

Recommend Projects

  • React photo React

    A declarative, efficient, and flexible JavaScript library for building user interfaces.

  • Vue.js photo Vue.js

    🖖 Vue.js is a progressive, incrementally-adoptable JavaScript framework for building UI on the web.

  • Typescript photo Typescript

    TypeScript is a superset of JavaScript that compiles to clean JavaScript output.

  • TensorFlow photo TensorFlow

    An Open Source Machine Learning Framework for Everyone

  • Django photo Django

    The Web framework for perfectionists with deadlines.

  • D3 photo D3

    Bring data to life with SVG, Canvas and HTML. 📊📈🎉

Recommend Topics

  • javascript

    JavaScript (JS) is a lightweight interpreted programming language with first-class functions.

  • web

    Some thing interesting about web. New door for the world.

  • server

    A server is a program made to process requests and deliver data to clients.

  • Machine learning

    Machine learning is a way of modeling and interpreting data that allows a piece of software to respond intelligently.

  • Game

    Some thing interesting about game, make everyone happy.

Recommend Org

  • Facebook photo Facebook

    We are working to build community through open source technology. NB: members must have two-factor auth.

  • Microsoft photo Microsoft

    Open source projects and samples from Microsoft.

  • Google photo Google

    Google ❤️ Open Source for everyone.

  • D3 photo D3

    Data-Driven Documents codes.