A command line tool for introducing random mutations into DNA sequences.
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Download: dunes.jar
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Compilation:
mvn clean install
java -jar dunes.jar
java -jar dunes.jar -h
Usage: dunes [-hV] -i=FILE [-m=m] [-n=n] [-o=<outputFolder>] [-y=y]
-h, --help Show this help message and exit.
-i, --inFile=FILE input fasta file with viral sequences to be mutated
-m, --mutation-rate=m mutation rate in substitutions per nucleotide per year
(s/n/y) (default: 4.1e-3)
-n, --mutants-number=n number of mutants for a strain (default: 1)
-o, --outFile=<outputFolder>
fasta file with mutated sequences (default: "<inFile
base>"Mut.fasta")
-V, --version Print version information and exit.
-y, --years=y years of evolution (default: 1)