alcoholicliverdisease's Introduction

Alcoholic Liver Disease (ALD): Medication and clinical parameters associated with course of disease

Analytics use case(s): Characterization, Population-Level Estimation
Study type: Clinical Application
Tags: Liver, Alcoholic liver disease, Drug, Gender
Study lead: Prof. Dr. Dr. Andreas Teufel, Medical Faculty Mannheim, Heidelberg University, Germany
Study lead forums tag: Andreas Teufel
Study start date: -
Study end date: -
Protocol: Here
Publications: -
Results explorer: -

Within this study we are interested in investigating new treatment options for patients with alcoholic liver disease respectively inside different sub groups as well as gender specific in respect of the overall survival of the patients.

How to run

Requirements for executing this package:
- DatabaseConnector ( >= 2.1.4 )
- SqlRender ( >= 1.5.2 )
- survival ( >= 2.42-4 )
The package needs to be installed into the R environment.
- with the devtools package inside a R session it could be done with
```
   devtools::install_github("ohdsi-studies/AlcoholicLiverDesease")
```
- from the command line on linux machines it could be done with
```
    R CMD build AlcoholicLiverDisease
    R CMD INSTALL AlcoholicLiverDisease_0.0.1.tar.gz
```

Then, within an interactive R session, execute the adapted commands below.

   library(AlcoholicLiverDisease)

   connectionDetails <- DatabaseConnector::createConnectionDetails(
       dbms = "sql server",          # DB Server type
       server = "localhost",         # URL / IP
       user = "<user>",              # user for connection
       password = "<password>",      # password for connection
       schema="<schema>",            # DB schema
       port = "1433"                 # port
   )

   execute(
       connectionDetails,
       sourceName="abbreviation"     # Abbreviation for the origin of DB
   )

The parameter sourceName is only used to connect the results with the origin. Therefore, please provide your institution or DB abbreviation as the sourceName parameter.

Once the execution is finished, the results will be placed as ZIP files inside the temporary directory of the R session. Please send them back to the study coordinator.