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Bioconductor Package - Metrics to estimate the level of similarity between two ChIP-Seq profiles

Home Page: http://bioconductor.org/packages/similaRpeak/

Makefile 0.19% R 99.81%
bioconductor bioconductor-package chip-profiles chip-seq metrics r

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similarpeak's Issues

Modify DIFF_POS_MAX metric

The current DIFF_POS_MAX metric is not appropriate when more than 1 peak is present.

The modifications includes:

1- Add tolerance value, in % of the max value, which will allow positions close to max value to be considered as max position.
2- Add threshold for the max value so the metric is not calculated when the max is low. Default : >0. When threshold not reached, NA value is returned.
3- Add threshold on position distance for 2 peak value to be considered as coming from a single peak. Default value = 100. When threshold not respected, NA value is returned.
4- When all threshold are respected, use the median position to calculate the position of the peak when more than one position present.

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