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Integration of cofactors with proteome-constrained model of Saccharomyces cerevisiae

License: GNU General Public License v3.0

MATLAB 91.19% Python 8.81%
genome-scale-models cofactor

cofactoryeast's Introduction

CofactorYeast

Introduction

This repository contains files for CofactorYeast. Cofactors, especially metal ions, have be integrated with proteome-constrained model of yeast.

Required Software

A functional Matlab installation.

The COBRA toolbox for MATLAB.

The solver SoPlex.

Reference

Chen Y, Li F, Mao J, Chen Y, Nielsen J. Yeast optimizes metal utilization based on metabolic network and enzyme kinetics. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2020154118. DOI:https://doi.org/10.1073/pnas.2020154118

Contact

  • Yu Chen (@Yu-sysbio), Chalmers University of Technology, Gothenburg, Sweden

Last update: 2021-06-01

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